d-β-Hydroxybutyric Dehydrogenase of Mitochondria
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چکیده
منابع مشابه
u-p-Hydroxybutyric Dehydrogenase of Mitochondria*
Although the reversible oxidation of free n-/3-hydroxybutyrate to acetoacetate in animal tissues was first observed many years ago (1, 2), relatively little is known about the properties and intracellular distribution of the dehydrogenase responsible for this reaction. In 1937 Green et al. (3) described a stereospecific diphosphopyridine nucleotide-linked n-P-hydroxybutyric dehydrogenase in res...
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Several different epithelial elements that have intense active transport or protein secretory functions were histochemically assayed in several dehydrogenase media by a recently perfected method. The mitochondria represented the only site of activity, not only when tested in the succinate and D-beta-hydroxybutyrate media, but also when tested in the lactate, malate, and isocitrate media. The re...
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Succinic semialdehyde dehydrogenase (SSADH) deficiency, a rare metabolic disorder of 4-aminobutyric acid degradation, has been identified in approximately 150 patients. Affected individuals accumulate large quantities of 4-hydroxybutyric acid, a compound with a wide range of neuropharmacological activities, in physiological fluids. As a first step in beginning an investigation of the molecular ...
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An accurate, simple colorimetric method for the determination of serum alpha-hydroxybutyric dehydrogenase activity is described. The method is suitable for routine laboratory use.
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1960
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)64641-1